Identification of Targetable Lesions in Anaplastic Thyroid Cancer by Genome Profiling

Identification of Targetable Lesions in Anaplastic Thyroid Cancer by Genome Profiling

Anaplastic thyroid cancer (ATC) is a rare and extremely malignant tumor with no available cure. The genetic landscape of this malignancy has not yet been fully explored. In this study, we performed whole exome sequencing and the RNA-sequencing of fourteen cases of ATC to delineate copy number change...

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Bibliographic Details
Main Authors: Naveen Ravi, Minjun Yang, Sigurdur Gretarsson, Caroline Jansson, Nektaria Mylona, Saskia R. Sydow, Eleanor L. Woodward, Lars Ekblad, Johan Wennerberg, Kajsa Paulsson
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
anaplastic thyroid cancer
whole exome sequencing
RNA-sequencing
formalin-fixed paraffin embedded tissues
fusion genes
somatic mutations
copy number alterations
<i>CCNE1</i>
Online Access:https://www.mdpi.com/2072-6694/11/3/402

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https://www.mdpi.com/2072-6694/11/3/402

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