Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium

Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium

The human gastrointestinal tract is immature at birth, yet must adapt to dramatic changes such as oral nutrition and microbial colonization. The confluence of these factors can lead to severe inflammatory disease in premature infants; however, investigating complex environment-host interactions is d...

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Bibliographic Details
Main Authors: David R Hill, Sha Huang, Melinda S Nagy, Veda K Yadagiri, Courtney Fields, Dishari Mukherjee, Brooke Bons, Priya H Dedhia, Alana M Chin, Yu-Hwai Tsai, Shrikar Thodla, Thomas M Schmidt, Seth Walk, Vincent B Young, Jason R Spence
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-11-01
Series:eLife
Subjects:
intestinal epithelium
microbiota
neonatal intestinal colonization
innate defense
epithelial barrier function
Online Access:https://elifesciences.org/articles/29132

Internet

https://elifesciences.org/articles/29132

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