Exacerbation of ichthyosis vulgaris phenotype by co-inheritance of STS and FLG mutations in a Chinese family with ichthyosis: a case report

Exacerbation of ichthyosis vulgaris phenotype by co-inheritance of STS and FLG mutations in a Chinese family with ichthyosis: a case report

Abstract Background X-linked ichthyosis (XLI) is a recessive keratinization condition caused by deficient activity of steroid-sulfatase due to mutations in steroid sulfatase (STS) gene located on the X chromosome. In contrast, ichthyosis vulgaris (IV) is caused by filaggrin deficiency due to semi-do...

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Bibliographic Details
Main Authors: Xiong Wang, Lu Tan, Na Shen, Yanjun Lu, Ying Zhang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Medical Genetics
Subjects:
STS
FLG
Ichthyosis
Mutation
Co-inheritance
Online Access:http://link.springer.com/article/10.1186/s12881-018-0642-5

Internet

http://link.springer.com/article/10.1186/s12881-018-0642-5

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