Macular impairment in mitochondrial diseases: a potential biomarker of disease severity

Abstract The high-energy demands of the retina are thought to contribute to its particular vulnerability to mitochondrial dysfunction. Photoreceptors are the cells with the higher oxygen consumption within the retina, and among these, the cones contain more mitochondria and have a higher energy dema...

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Bibliographic Details
Main Authors: Guido Primiano, Edoardo Abed, Giovanni Corbo, Angelo Maria Minnella, Serenella Servidei, Catello Vollono, Maria Cristina Savastano, Benedetto Falsini
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-65482-3