IRES-mediated translation of membrane proteins and glycoproteins in eukaryotic cell-free systems.

Internal ribosome entry site (IRES) elements found in the 5' untranslated region of mRNAs enable translation initiation in a cap-independent manner, thereby representing an alternative to cap-dependent translation in cell-free protein expression systems. However, IRES function is largely specie...

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Bibliographic Details
Main Authors: Andreas K Brödel, Andrei Sonnabend, Lisa O Roberts, Marlitt Stech, Doreen A Wüstenhagen, Stefan Kubick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869664?pdf=render