Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses

Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses

Potentially harmful stimuli are detected at the skin by nociceptor sensory neurons that drive rapid protective withdrawal reflexes and pain. We set out to define, at a millisecond timescale, the relationship between the activity of these sensory neurons and the resultant behavioral output. Brief opt...

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Bibliographic Details
Main Authors: Liam E. Browne, Alban Latremoliere, Brendan P. Lehnert, Alyssa Grantham, Catherine Ward, Chloe Alexandre, Michael Costigan, Frédéric Michoud, David P. Roberson, David D. Ginty, Clifford J. Woolf
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Cell Reports
Subjects:
pain
nociception
reflexes
quantitative behavior
optogenetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717308215

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717308215

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