Effects of Carbenoxolone on the Canine Pituitary-Adrenal Axis.

Cushing's disease caused by pituitary corticotroph adenoma is a common endocrine disease in dogs. A characteristic biochemical feature of corticotroph adenomas is their relative resistance to suppressive negative feedback by glucocorticoids. The abnormal expression of 11beta-hydroxysteroid dehy...

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Bibliographic Details
Main Authors: Takahiro Teshima, Hirotaka Matsumoto, Tomoko Okusa, Yumi Nakamura, Hidekazu Koyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4532459?pdf=render