HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors

HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors

Abstract Background Approximately one in five breast cancers are driven by amplification and overexpression of the human epidermal growth factor receptor 2 (HER2) receptor kinase, and HER2-enriched (HER2E) is one of four major transcriptional subtypes of breast cancer. We set out to understand the g...

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Bibliographic Details
Main Authors: Anneleen Daemen, Gerard Manning
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Cancer
Amplification
ERBB2
Genomic characterization
PAM50
Online Access:http://link.springer.com/article/10.1186/s13058-018-0933-y

Internet

http://link.springer.com/article/10.1186/s13058-018-0933-y

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