Chronic Blockade of Brain Endothelin Receptor Type-A (ETA) Reduces Blood Pressure and Prevents Catecholaminergic Overactivity in the Right Olfactory Bulb of DOCA-Salt Hypertensive Rats

Chronic Blockade of Brain Endothelin Receptor Type-A (ETA) Reduces Blood Pressure and Prevents Catecholaminergic Overactivity in the Right Olfactory Bulb of DOCA-Salt Hypertensive Rats

Overactivity of the sympathetic nervous system and central endothelins (ETs) are involved in the development of hypertension. Besides the well-known brain structures involved in the regulation of blood pressure like the hypothalamus or locus coeruleus, evidence suggests that the olfactory bulb (OB)...

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Bibliographic Details
Main Authors: Luis R. Cassinotti, María J. Guil, Mercedes I. Schöller, Mónica P. Navarro, Liliana G. Bianciotti, Marcelo S. Vatta
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
hypertension
systolic blood pressure
endothelin
BQ610
tyrosine hydroxylase
Online Access:http://www.mdpi.com/1422-0067/19/3/660

Internet

http://www.mdpi.com/1422-0067/19/3/660

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