Nano Ellagic Acid Counteracts Cisplatin-Induced Upregulation in OAT1 and OAT3: A Possible Nephroprotection Mechanism

Nano Ellagic Acid Counteracts Cisplatin-Induced Upregulation in OAT1 and OAT3: A Possible Nephroprotection Mechanism

Cisplatin is an anticancer drug commonly used for solid tumors. However, it causes nephrotoxicity. OAT1 and OAT3 are organic anion transporters known to contribute to the uptake of cisplatin into renal tubular cells. The present study was designed to examine the protective role of ellagic acid nanof...

Full description

Bibliographic Details
Main Authors: Thikryat Neamatallah, Nagla El-Shitany, Aymn Abbas, Basma G. Eid, Steve Harakeh, Soad Ali, Shaker Mousa
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
cisplatin
ellagic acid nano
nephrotoxicity
organic anion transporters
oxidative stress
Online Access:https://www.mdpi.com/1420-3049/25/13/3031

Internet

https://www.mdpi.com/1420-3049/25/13/3031

Similar Items