Viral dosing of influenza A infection reveals involvement of RIPK3 and FADD, but not MLKL

Abstract RIPK3 was reported to play an important role in the protection against influenza A virus (IAV) in vivo. Here we show that the requirement of RIPK3 for protection against IAV infection in vivo is only apparent within a limited dose range of IAV challenge. We found that this protective outcom...

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Bibliographic Details
Main Authors: Teodora Oltean, Emily Van San, Tatyana Divert, Tom Vanden Berghe, Xavier Saelens, Jonathan Maelfait, Nozomi Takahashi, Peter Vandenabeele
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03746-0