Jejunal Insulin Signalling Is Increased in Morbidly Obese Subjects with High Insulin Resistance and Is Regulated by Insulin and Leptin

Jejunal Insulin Signalling Is Increased in Morbidly Obese Subjects with High Insulin Resistance and Is Regulated by Insulin and Leptin

Little is known about the jejunal insulin signalling pathways in insulin resistance/diabetes states and their possible regulation by insulin/leptin. We study in jejunum the relation between insulin signalling and insulin resistance in morbidly obese subjects with low (MO-low-IR) or with high insulin...

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Bibliographic Details
Main Authors: Carolina Gutierrez-Repiso, Ailec Ho-Plagaro, Concepción Santiago-Fernandez, Sara Garcia-Serrano, Francisca Rodríguez-Pacheco, Sergio Valdes, Lourdes Garrido-Sanchez, Cristina Rodríguez-Díaz, Carlos López-Gómez, Francisco J. Moreno-Ruiz, Guillermo Alcain-Martinez, Amandine Gautier-Stein, Gilles Mithieux, Eduardo Garcia-Fuentes
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Journal of Clinical Medicine
Subjects:
insulin resistance
jejunum
morbid obesity
leptin
Online Access:https://www.mdpi.com/2077-0383/9/1/196

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https://www.mdpi.com/2077-0383/9/1/196

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