Integrated multimodal imaging of dynamic bone-tumor alterations associated with metastatic prostate cancer.

Bone metastasis occurs for men with advanced prostate cancer which promotes osseous growth and destruction driven by alterations in osteoblast and osteoclast homeostasis. Patients can experience pain, spontaneous fractures and morbidity eroding overall quality of life. The complex and dynamic cellul...

Full description

Bibliographic Details
Main Authors: Jean-Christophe Brisset, Benjamin A Hoff, Thomas L Chenevert, Jon A Jacobson, Jennifer L Boes, Stefanie Galbán, Alnawaz Rehemtulla, Timothy D Johnson, Kenneth J Pienta, Craig J Galbán, Charles R Meyer, Timothy Schakel, Klaas Nicolay, Ajjai S Alva, Maha Hussain, Brian D Ross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4393258?pdf=render