Astrocytes are mainly responsible for the polyunsaturated fatty acid enrichment in blood–brain barrier endothelial cells in vitro

To determine the respective roles of endothelial cells from brain capillaries and astrocytes in the conversion of circulating 18:2n–6 and 18:3n–3 into 20:4n–6 and 22:6n–3, respectively, a coculture of the two cell types mimicking the in vivo blood–brain barrier was used. During the culture period, e...

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Bibliographic Details
Main Authors: N. Bernoud, L. Fenart, C. Bénistant, J.F. Pageaux, M.P. Dehouck, P. Molière, M. Lagarde, R. Cecchelli, J. Lecerf
Format: Article
Language:English
Published: Elsevier 1998-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520321696