Lamina Associated Domains and Gene Regulation in Development and Cancer

The nuclear lamina (NL) is a thin meshwork of filaments that lines the inner nuclear membrane, thereby providing a platform for chromatin binding and supporting genome organization. Genomic regions contacting the NL are lamina associated domains (LADs), which contain thousands of genes that are lowl...

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Bibliographic Details
Main Authors: Silke J. A. Lochs, Samy Kefalopoulou, Jop Kind
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/3/271