A deep sequencing approach to uncover the miRNOME in the human heart.

MicroRNAs (miRNAs) are a class of non-coding RNAs of ∼22 nucleotides in length, and constitute a novel class of gene regulators by imperfect base-pairing to the 3'UTR of protein encoding messenger RNAs. Growing evidence indicates that miRNAs are implicated in several pathological processes in m...

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Main Authors: Stefanos Leptidis, Hamid El Azzouzi, Sjoukje I Lok, Roel de Weger, Servé Olieslagers, Natasja Kisters, Gustavo J Silva, Stephane Heymans, Edwin Cuppen, Eugene Berezikov, Leon J De Windt, Paula da Costa Martins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3583901?pdf=render