Group B streptococcus GAPDH is released upon cell lysis, associates with bacterial surface, and induces apoptosis in murine macrophages.

Glyceraldehyde 3-phosphate dehydrogenases (GAPDH) are cytoplasmic glycolytic enzymes that, despite lacking identifiable secretion signals, have been detected at the surface of several prokaryotic and eukaryotic organisms where they exhibit non-glycolytic functions including adhesion to host componen...

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Bibliographic Details
Main Authors: Liliana Oliveira, Pedro Madureira, Elva Bonifácio Andrade, Abdelouhab Bouaboud, Eric Morello, Paula Ferreira, Claire Poyart, Patrick Trieu-Cuot, Shaynoor Dramsi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3264557?pdf=render