Thresholds of oxidative stress in newly diagnosed diabetic patients on intensive glucose-control therapy.

Cellular and animal studies suggest that oxidative stress could be the central defect underlying both beta-cell dysfunction and insulin resistance in type 2 diabetes mellitus. A reduction of glycemic stress in diabetic patients on therapy alleviates systemic oxidative stress and improves insulin res...

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Bibliographic Details
Main Authors: Rashmi Kulkarni, Jhankar Acharya, Saroj Ghaskadbi, Pranay Goel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4074157?pdf=render