Observation of Enhanced Dissociative Photochemistry in the Non-Native Nucleobase 2-Thiouracil

Observation of Enhanced Dissociative Photochemistry in the Non-Native Nucleobase 2-Thiouracil

We present the first study to measure the dissociative photochemistry of 2-thiouracil (2-TU), an important nucleobase analogue with applications in molecular biology and pharmacology. Laser photodissociation spectroscopy is applied to the deprotonated and protonated forms of 2-TU, which are produced...

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Bibliographic Details
Main Authors: Kelechi O. Uleanya, Rosaria Cercola, Maria Nikolova, Edward Matthews, Natalie G. K. Wong, Caroline E. H. Dessent
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
2-thiouracil
free-radicals
non-native nucleobase
excited states
phototherapy
Online Access:https://www.mdpi.com/1420-3049/25/14/3157

Internet

https://www.mdpi.com/1420-3049/25/14/3157

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