Evaluation of HPV16 E7 expression in head and neck carcinoma cell lines and clinical specimens

Abstract Human papillomavirus (HPV) 16 infection in the oropharynx is one of the major risk factors for oropharyngeal carcinoma. Although the HPV E6 and E7 proteins are known to have a role in head and neck carcinogenesis, whether their expression is maintained once the tumour has developed still re...

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Bibliographic Details
Main Authors: Koji Kitamura, Keisuke Nimura, Rie Ito, Kotaro Saga, Hidenori Inohara, Yasufumi Kaneda
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78345-8