MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.

MicroRNAs (miRNAs) are critical regulators of transcriptional and post-transcriptional gene silencing, which are involved in multiple developmental processes in many organisms. Apart from miRNAs, mouse germ cells express another type of small RNA, piwi-interacting RNAs (piRNAs). Although it has been...

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Bibliographic Details
Main Authors: Katsuhiko Hayashi, Susana M Chuva de Sousa Lopes, Masahiro Kaneda, Fuchou Tang, Petra Hajkova, Kaiqin Lao, Donal O'Carroll, Partha P Das, Alexander Tarakhovsky, Eric A Miska, M Azim Surani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2254191?pdf=render