An Explorative Study on Monocyte Reprogramming in the Context of Periodontitis In Vitro and In Vivo

An Explorative Study on Monocyte Reprogramming in the Context of Periodontitis In Vitro and In Vivo

AimsPeriodontitis is an independent risk factor for cardiovascular disease, but the mechanistic link is not fully understood. In atherosclerotic cardiovascular disease, monocytes can adopt a persistent hyperresponsive phenotype, termed trained immunity. We hypothesized that periodontitis-associated...

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Bibliographic Details
Main Authors: Marlies P. Noz, Adelina S. Plachokova, Esther M.M. Smeets, Erik H. J. G. Aarntzen, Siroon Bekkering, Prya Vart, Leo A. B. Joosten, Mihai G. Netea, Niels P. Riksen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
periodontitis
Porphyromonas gingivalis
trained immunity
inflammation
cardiovascular disease
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.695227/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.695227/full

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