Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion

Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion

Abstract Background Cyclin-dependent kinase-like 1 (CDKL1) is a member of the cell division control protein 2-related serine–threonine protein kinase family. It is known to occur in various malignant tumors, but its role in neuroblastoma (NB) remains unclear. Methods We constructed a CDKL1-silenced...

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Bibliographic Details
Main Authors: Weiyi Li, Jing Cao, Jian Liu, Wenli Chu, Congqing Zhang, Shuiling Chen, Zefeng Kang
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Cellular & Molecular Biology Letters
Subjects:
Neuroblastoma
SH-SY5Y
CDKL1
Proliferation
Migration
Invasion
Online Access:http://link.springer.com/article/10.1186/s11658-019-0139-z

Internet

http://link.springer.com/article/10.1186/s11658-019-0139-z

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