Vibrating Mesh Nebulisation of Pro-Antimicrobial Peptides for Use in Cystic Fibrosis

Vibrating Mesh Nebulisation of Pro-Antimicrobial Peptides for Use in Cystic Fibrosis

Background: There has been considerable interest in the use of antimicrobial peptides (AMPs) as antimicrobial therapeutics in many conditions including cystic fibrosis (CF). The aim of this study is to determine if the prodrugs of AMPs (pro-AMPs) can be delivered to the lung by a vibrating mesh nebu...

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Bibliographic Details
Main Authors: Éanna Forde, Graeme Kelly, Louise Sweeney, Deirdre Fitzgerald-Hughes, Ronan MacLoughlin, Marc Devocelle
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Pharmaceutics
Subjects:
aerosol
antibiotics
antimicrobial peptides
cystic fibrosis
inhalation
peptide drugs
pulmonary drug delivery
prodrugs
vibrating mesh nebuliser
Online Access:https://www.mdpi.com/1999-4923/11/5/239

Internet

https://www.mdpi.com/1999-4923/11/5/239

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