Epigenetic Control of Cytomegalovirus Latency and Reactivation

Epigenetic Control of Cytomegalovirus Latency and Reactivation

Cytomegalovirus (CMV) gene expression is repressed in latency due to heterochromatinization of viral genomes. In murine CMV (MCMV) latently infected mice, viral genomes are bound to histones with heterochromatic modifications, to enzymes that mediate these modifications, and to adaptor proteins that...

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Bibliographic Details
Main Authors: Mary Hummel, Shixian Yan, Zheng Zhang, Michael Abecassis, Xue-feng Liu, Xueqiong Wang
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:Viruses
Subjects:
cytomegalovirus
latency
reactivation
epigenetics
chromatin
intrinsic immunity
transplantation
Online Access:http://www.mdpi.com/1999-4915/5/5/1325

Internet

http://www.mdpi.com/1999-4915/5/5/1325

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