Expression of tumor necrosis factor-alpha-mediated genes predicts recurrence-free survival in lung cancer.

In this study, we conducted a meta-analysis on high-throughput gene expression data to identify TNF-α-mediated genes implicated in lung cancer. We first investigated the gene expression profiles of two independent TNF-α/TNFR KO murine models. The EGF receptor signaling pathway was the top pathway as...

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Bibliographic Details
Main Authors: Baohua Wang, Ning Song, Tong Yu, Lianya Zhou, Helin Zhang, Lin Duan, Wenshu He, Yihua Zhu, Yunfei Bai, Miao Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4280165?pdf=render