Influence of Low Protein Diet-Induced Fetal Growth Restriction on the Neuroplacental Corticosterone Axis in the Rat

Influence of Low Protein Diet-Induced Fetal Growth Restriction on the Neuroplacental Corticosterone Axis in the Rat

Objectives: Placental steroid metabolism is linked to the fetal hypothalamus-pituitary-adrenal axis. Intrauterine growth restriction (IUGR) might alter this cross-talk and lead to maternal stress, in turn contributing to the pathogenesis of anxiety-related disorders of the offspring, which might be...

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Bibliographic Details
Main Authors: Marius Schmidt, Manfred Rauh, Matthias C. Schmid, Hanna Huebner, Matthias Ruebner, Rainer Wachtveitl, Nada Cordasic, Wolfgang Rascher, Carlos Menendez-Castro, Andrea Hartner, Fabian B. Fahlbusch
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Endocrinology
Subjects:
IUGR intrauterine growth restriction
steroids
brain
placenta
Hsd11b2
rat model
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00124/full

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https://www.frontiersin.org/article/10.3389/fendo.2019.00124/full

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