Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice

Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice

<p>Abstract</p> <p>Background</p> <p>The immune mechanisms associated with infection-induced disease exacerbations in asthma and COPD are not fully understood. Toll-like receptor (TLR) 3 has an important role in recognition of double-stranded viral RNA, which leads to t...

Full description

Bibliographic Details
Main Authors: Alexopoulou Lena, Flavell Richard A, Bunting Rachel A, Marsters Paul A, Murray Lynne A, Bugelski Peter J, Egenolf Devon D, Lamb Roberta J, Smalley Karen A, Raymond Holly A, Seideman Jonathan, Stowell Nicole C, San Mateo Lani R, Griswold Don E, Sarisky Robert T, Mbow M Lamine, Das Anuk M
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/10/1/43

Internet

http://respiratory-research.com/content/10/1/43

Similar Items