Distinct Roles of Mitochondrial HIGD1A and HIGD2A in Respiratory Complex and Supercomplex Biogenesis

Distinct Roles of Mitochondrial HIGD1A and HIGD2A in Respiratory Complex and Supercomplex Biogenesis

Summary: The mitochondrial respiratory chain enzymes are organized as individual complexes and supercomplexes, whose biogenesis remains to be fully understood. To disclose the role of the human Hypoxia Inducible Gene Domain family proteins HIGD1A and HIGD2A in these processes, we generate and charac...

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Bibliographic Details
Main Authors: Alba Timón-Gómez, Joshua Garlich, Rosemary A. Stuart, Cristina Ugalde, Antoni Barrientos
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Cell Reports
Subjects:
mitochondrial respiratory chain
supercomplexes
respirasomes
HIGD1A
HIGD2A
COX7A2L
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720305568

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http://www.sciencedirect.com/science/article/pii/S2211124720305568

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