The degradation of airway tight junction protein under acidic conditions is probably mediated by transient receptor potential vanilloid 1 receptor
Acidic airway microenvironment is one of the representative pathophysiological features of chronic inflammatory respiratory diseases. Epithelial barrier function is maintained by TJs (tight junctions), which act as the first physical barrier against the inhaled substances and pathogens of airway. As...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Portland Press, Biochemical Society
2013-10-01
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| Series: | Bioscience Reports |
| Subjects: | |
| Online Access: | http://www.bioscirep.org/bsr/033/e078/bsr033e078.htm |