A novel mode of control of nickel uptake by a multifunctional metallochaperone.

Cellular metal homeostasis is a critical process for all organisms, requiring tight regulation. In the major pathogen Helicobacter pylori, the acquisition of nickel is an essential virulence determinant as this metal is a cofactor for the acid-resistance enzyme, urease. Nickel uptake relies on the N...

Full description

Bibliographic Details
Main Authors: Milica Denic, Evelyne Turlin, Valérie Michel, Frédéric Fischer, Mozhgan Khorasani-Motlagh, Deborah Zamble, Daniel Vinella, Hilde de Reuse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009193