Trans-Fatty Acids Aggravate Obesity, Insulin Resistance and Hepatic Steatosis in C57BL/6 Mice, Possibly by Suppressing the IRS1 Dependent Pathway

Trans-Fatty Acids Aggravate Obesity, Insulin Resistance and Hepatic Steatosis in C57BL/6 Mice, Possibly by Suppressing the IRS1 Dependent Pathway

Trans-fatty acid consumption has been reported as a risk factor for metabolic disorders and targeted organ damages. Nonetheless, little is known about the roles and mechanisms of trans-fatty acids in obesity, insulin resistance (IR) and hepatic steatosis. Adult C57BL/6 male mice were fed with four d...

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Bibliographic Details
Main Authors: Xiaona Zhao, Cheng Shen, Hong Zhu, Cong Wang, Xiangwei Liu, Xiaolei Sun, Shasha Han, Peng Wang, Zhen Dong, Xin Ma, Kai Hu, Aijun Sun, Junbo Ge
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Molecules
Subjects:
trans-fatty acid
obesity
insulin resistance
hepatic steatosis
Online Access:http://www.mdpi.com/1420-3049/21/6/705

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http://www.mdpi.com/1420-3049/21/6/705

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