The receptor for advanced glycation end products (RAGE) contributes to the progression of emphysema in mice.

Several recent clinical studies have implied a role for the receptor for advanced glycation end products (RAGE) and its variants in chronic obstructive pulmonary disease (COPD). In this study we have defined a role for RAGE in the pathogenesis of emphysema in mice. RAGE deficient mice (RAGE-/-) expo...

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Bibliographic Details
Main Authors: Nisha Sambamurthy, Adriana S Leme, Tim D Oury, Steven D Shapiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364508?pdf=render