Small GTPase Rap1 Is Essential for Mouse Development and Formation of Functional Vasculature.

BACKGROUND:Small GTPase Rap1 has been implicated in a number of basic cellular functions, including cell-cell and cell-matrix adhesion, proliferation and regulation of polarity. Evolutionarily conserved, Rap1 has been studied in model organisms: yeast, Drosophila and mice. Mouse in vivo studies impl...

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Bibliographic Details
Main Authors: Magdalena Chrzanowska-Wodnicka, Gilbert C White, Lawrence A Quilliam, Kevin J Whitehead
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4694701?pdf=render