Xenopus reduced folate carrier regulates neural crest development epigenetically.

Folic acid deficiency during pregnancy causes birth neurocristopathic malformations resulting from aberrant development of neural crest cells. The Reduced folate carrier (RFC) is a membrane-bound receptor for facilitating transfer of reduced folate into the cells. RFC knockout mice are embryonic let...

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Bibliographic Details
Main Authors: Jiejing Li, Yu Shi, Jian Sun, Yanfeng Zhang, Bingyu Mao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3212533?pdf=render