High-Level Fosfomycin Resistance in Vancomycin-Resistant Enterococcus faecium

High-Level Fosfomycin Resistance in Vancomycin-Resistant Enterococcus faecium

Of 890 vancomycin-resistant Enterococcus faecium isolates obtained by rectal screening from patients in Pittsburgh, Pennsylvania, USA, 4 had MICs >1,024 μg/mL for fosfomycin. These isolates had a Cys119Asp substitution in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase. This su...

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Bibliographic Details
Main Authors: Yan Guo, Adam D. Tomich, Christi L. McElheny, Vaughn S. Cooper, Amelia Tait-Kamradt, Min Chen, Fupin Hu, Louis B. Rice, Nicolas Sluis-Cremer, Yohei Doi
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2017-11-01
Series:Emerging Infectious Diseases
Subjects:
fosfomycin
fosfomycin resistance
vancomycin
vancomycin resistance
Enterococcus faecium
bacteria
Online Access:https://wwwnc.cdc.gov/eid/article/23/11/17-1130_article

Internet

https://wwwnc.cdc.gov/eid/article/23/11/17-1130_article

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