Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injuryResearch in context

Background: Soluble amyloid-β oligomer (AβO) induced deleterious cascades have recently been considered to be the initiating pathologic agents of Alzheimer's disease (AD). However, little is known about the neurotoxicity and production of different AβOs. Understanding the production and spread...

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Bibliographic Details
Main Authors: Wei Wang, Ting-ting Hou, Long-fei Jia, Qiao-qi Wu, Mei-na Quan, Jian-ping Jia
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641930194X