Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions

Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions

Human proximal tubular epithelial cells (PTEC) of the kidney are known to respond to and mediate the disease process in a wide range of kidney diseases, yet their exosomal production and exosome molecular cargo remain a mystery. Here we investigate, for the first time, the production and molecular c...

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Bibliographic Details
Main Authors: Xiangju Wang, Ray Wilkinson, Katrina Kildey, Jeremy Potriquet, Jason Mulvenna, Richard J. Lobb, Andreas Möller, Nicole Cloonan, Pamela Mukhopadhyay, Andrew J. Kassianos, Helen Healy
Format: Article
Language:English
Published: Taylor & Francis Group 2017-12-01
Series:Journal of Extracellular Vesicles
Subjects:
Human proximal tubular epithelial cells
exosomes
inflammation
hypoxia
microRNA
Online Access:http://dx.doi.org/10.1080/20013078.2017.1314073

Internet

http://dx.doi.org/10.1080/20013078.2017.1314073

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