Piperlongumine induces pancreatic cancer cell death by enhancing reactive oxygen species and DNA damage

Pancreatic cancer is one of the most deadly cancers with a nearly 95% mortality rate. The poor response of pancreatic cancer to currently available therapies and the extremely low survival rate of pancreatic cancer patients point to a critical need for alternative therapeutic strategies. The use of...

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Bibliographic Details
Main Authors: Harsharan Dhillon, Shireen Chikara, Katie M. Reindl
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Toxicology Reports
Subjects:
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014000316