High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice

High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice

Abstract Background Titanium dioxide nanoparticles (TiO2 NPs) have a wide range of applications in several industrial and biomedical domains. Based on the evidence, the workers exposed to inhaled nanosized TiO2 powder are more susceptible to the risks of developing respiratory diseases. Accordingly,...

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Bibliographic Details
Main Authors: Shaza Abdulnasser Harfoush, Matthias Hannig, Duc Dung Le, Sebastian Heck, Maximilian Leitner, Albert Joachim Omlor, Isabella Tavernaro, Annette Kraegeloh, Ralf Kautenburger, Guido Kickelbick, Andreas Beilhack, Markus Bischoff, Juliane Nguyen, Martina Sester, Robert Bals, Quoc Thai Dinh
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Respiratory Research
Subjects:
Asthma
Titanium dioxide nanoparticles
Ovalbumin
Airway inflammation
Hyperresponsiveness, systemic uptake
Online Access:http://link.springer.com/article/10.1186/s12931-020-01386-0

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http://link.springer.com/article/10.1186/s12931-020-01386-0

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