Astragaloside IV Alleviates the Experimental DSS-Induced Colitis by Remodeling Macrophage Polarization Through STAT Signaling

Astragaloside IV Alleviates the Experimental DSS-Induced Colitis by Remodeling Macrophage Polarization Through STAT Signaling

Inflammatory bowel disease (IBD) is characterized by chronic and relapsing intestinal inflammation, which currently lacks safe and effective medicine. Some previous studies indicated that Astragaloside IV (AS-IV), a natural saponin extracted from the traditional Chinese medicine herb Ligusticum chua...

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Bibliographic Details
Main Authors: Lianlian Tian, Jun-Long Zhao, Jian-Qin Kang, Shi-bo Guo, Nini Zhang, Lei Shang, Ya-Long Zhang, Jian Zhang, Xun Jiang, Yan Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
inflammatory bowel disease
astragaloside IV (AS-IV)
macrophages polarization
STAT signaling
pro-resolving macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.740565/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.740565/full

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