Aquaporin-2 Promoter Is Synergistically Regulated by Nitric Oxide and Nuclear Factor of Activated T Cells
Background/Aims: We have previously shown that aquaporin-2 (AQP2) is down-regulated in the renal medulla of rats made hypertensive by chronic inhibition of nitric oxide synthase. It has been shown that AQP2 expression is regulated by the calcineurin/nuclear factor of activated T cells (NFATc). Nitri...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Karger Publishers
2011-10-01
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Series: | Nephron Extra |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/333066 |