Aquaporin-2 Promoter Is Synergistically Regulated by Nitric Oxide and Nuclear Factor of Activated T Cells

Background/Aims: We have previously shown that aquaporin-2 (AQP2) is down-regulated in the renal medulla of rats made hypertensive by chronic inhibition of nitric oxide synthase. It has been shown that AQP2 expression is regulated by the calcineurin/nuclear factor of activated T cells (NFATc). Nitri...

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Bibliographic Details
Main Authors: María F. Albertoni Borghese, Layne M. Bettini, Carlos H. Nitta, Sergio de Frutos, Mónica Majowicz, Laura V. Gonzalez Bosc
Format: Article
Language:English
Published: Karger Publishers 2011-10-01
Series:Nephron Extra
Subjects:
Online Access:http://www.karger.com/Article/FullText/333066