Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle

Abstract Skeletal muscle has the remarkable ability to regenerate. However, with age and disease muscle strength and function decline. Myofiber size, which is affected by injury and disease, is a critical measurement to assess muscle health. Here, we test and apply Cellpose, a recently developed dee...

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Bibliographic Details
Main Authors: Ariel Waisman, Alessandra Marie Norris, Martín Elías Costa, Daniel Kopinke
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91191-6