Immunologic targeting of FOXP3 in inflammatory breast cancer cells.

Immunologic targeting of FOXP3 in inflammatory breast cancer cells.

The forkhead transcription factor FOXP3 is necessary for induction of regulatory T lymphocytes (Tregs) and their immunosuppressive function. We have previously demonstrated that targeting Tregs by vaccination of mice with murine FOXP3 mRNA-transfected dendritic cells (DCs) elicits FOXP3-specific T c...

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Bibliographic Details
Main Authors: Smita Nair, Amy J Aldrich, Eoin McDonnell, Qing Cheng, Anshu Aggarwal, Pujan Patel, Monique M Williams, David Boczkowski, H Kim Lyerly, Michael A Morse, Gayathri R Devi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3544902?pdf=render

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http://europepmc.org/articles/PMC3544902?pdf=render

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