Histopathological characteristics of breast cancer and evaluation of ER alpha and Her-2neu using immunohistochemical and RT-PCR techniques

Background and purpose: Oestrogen receptor (ER) and HER (human epidermal growth factor receptor) family signaling pathways are fundamental to guide treatment and determine prognosis. Categorizing breast cancer tumors as ER and Her-2 positive or negative is usually performed by immunohistochemistry (...

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Bibliographic Details
Main Authors: Eman El-Abd, Cecil A. Matta, Manal Sheta, Yasser El-Kerm, Shimaa Sakr
Format: Article
Language:English
Published: Taylor & Francis Group 2014-09-01
Series:Alexandria Journal of Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S209050681400030X