Mechanism of collagen folding propagation studied by Molecular Dynamics simulations.

Collagen forms a characteristic triple helical structure and plays a central role for stabilizing the extra-cellular matrix. After a C-terminal nucleus formation folding proceeds to form long triple-helical fibers. The molecular details of triple helix folding process is of central importance for an...

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Bibliographic Details
Main Authors: Julian Hartmann, Martin Zacharias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009079