Synthetical Application of Alkyl 2-isothiocyanatocarboxylates. A Simple Synthesis of 5-Substituted-3-amino-2-thioxo-4-imidazolidinones (3-Amino-2-thiohydantoins)
The title 3-amino-2-thiohydantoins 3 has been prepared in very good yields by the reaction of alkyl isothiocynatocarboxylates 1 with hydrazine hydrate.The synthesis of starting isothiocyanates as well as spectral data of 3-aminothiohydantoins and alkyl isothiocyanatocarboxylates has been presented.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
1999-09-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/4/10/279/ |