Origin and Evolution of Deleterious Mutations in Horses

Domestication has changed the natural evolutionary trajectory of horses by favoring the reproduction of a limited number of animals showing traits of interest. Reduced breeding stocks hampered the elimination of deleterious variants by means of negative selection, ultimately inflating mutational loa...

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Bibliographic Details
Main Authors: Ludovic Orlando, Pablo Librado
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/10/9/649