A novel chiral GC/MS method for the analysis of fluoxetine and norfluoxetine enantiomers in biological fluids

A novel chiral GC/MS method for the analysis of fluoxetine and norfluoxetine enantiomers in biological fluids

Aims: A novel robust chiral gas chromatographic/mass spectrometric (GC/MS) method for the separation and measurement of fluoxetine and norfluoxetine enantiomers in urine and plasma was developed. Materials and Methods: The drug was extracted from the samples by a liquid-liquid technique, using chlor...

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Bibliographic Details
Main Authors: Janet Mifsud, Lino J Sghendo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Chiral
cyclodextrin
fluoxetine
GCMS
urine
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=3;spage=236;epage=245;aulast=Mifsud

Internet

http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=3;spage=236;epage=245;aulast=Mifsud

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