Therapeutic effect of valsartan against doxorubicin-induced renal toxicity in rats

Objective(s): Doxorubicin (DXR)-induces glomerular atrophy and fibrosis in rat kidneys. The objective of the current study was to investigate the protective effects of valsartan on DXR-induced glomerular toxicity and its mechanisms of actions in rats. Materials and Methods: Male Sprague-Dawley (SD)...

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Bibliographic Details
Main Authors: Hai-Xia Liu, Jin Li, Qi-Xiong Li
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2019-03-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_12203_3c0df9b265f5dcc1ffb9b99ed03e16e2.pdf